2016年9月14日星期三

The Use of Dianabol as a Supplement

This article was originally intended to be a history of the anabolic steroid dianabol and it's usage in bodybuilding, but there is little real evidence of how it was used in previous decades. However, in the course of research, I have come to the conclusion that current use of dianabol as a supplement is not as efficient as it could be. Most of the modern thoughts on dianabol use reflect around myths and irrelevant scientific studies; this article attempts to explain new ways of thinking on dianabol usage using scientific evidence and people's experiences.



Dianabol (or dbol as it's commonly called) is one of the most commonly used oral steroids. Its chemical name is methanedienone or methandrostenolone and there are many different pharmaceutical and generic varieties including Anabol and Naposim. In this article we look at lower dose usage of dianabol as a supplement, as opposed to using pro-hormones or pro-steroids.

Liver Toxicity of Dianabol

The 17 alpha-alkylated properties of methanedienone do make it liver toxic, but this, I believe, is overstated as most of the evidence of its toxicity comes from studies on individuals and not from studies on large groups of dianabol-using bodybuilders. One study on rats (1) showed that regardless of dose or time of administration, dianabol produces changes in enzymatic activity, which leads to hypertrophy of hepatocytes; which basically shows that dianabol is toxic to the liver. But in another study (2) Nerobol (Russian Dianabol) was found to favour a rapid normalisation of functional and metabolic disorders of the liver, which contradicts the earlier evidence. This shows that the whole idea of dianabol being dangerous is in no way as bad as some would make out.

Benefits of Dianabol Use

Dianabol has been shown to increase anaerobic glycolysis (3), which increases lactic acid build up in the body. This is beneficial because lactic acid is used by the muscles to form glycogen, which in turn provides energy in anaerobic metabolism. Lactic acid is also a key chemical in the disposal of dietary carbohydrates, which means you are less likely to get fat while using dianabol.

A study on osteoporosis (4) showed that at a dosage of just 2.5mg per day for 9 months dianabol was more effective than calcium supplementation in reducing osteoporotic activity, it was also shown to increase muscle mass more effectively. Another study on osteoporosis (5) which lasted 24 months, showed just how dianabol works on osteoporosis; dianabol increased total body calcium, and also total body potassium. This may not mean much to you as a bodybuilder, but the actions of calcium are very important to bodybuilders, as it transports large numbers of amino acids and also creatine and these two things are vital in muscle growth. Potassium is also very important, as it assists in muscle contractions, transmitting nerve signals, and insulin release; so it is also a very anabolic substance.

One very interesting study (6), although not significant in bodybuilding terms, showed that dianabol increases the sensitivity of laryngeal tumour cells to radiotherapy, and concluded 'recommending this hormone to be used during radiotherapy of patients with the laryngeal cancer'.

How to Cycle Dianabol

To create a cycle for dianabol that is based around using it more as a supplement than a steroid, we first need to look at the current trend for cycling dianabol and analyse what is wrong with it. An average cycle of Dianabol is usually structured as 25-40mg split throughout each day for 4-6 weeks, either alone or stacked with other steroids.

Firstly a dose of 25mg or more commonly causes water retention. It is well known that dianabol does aromatise quite easily, and most of the water retention is usually attributed to a build up of excess estrogen. However, it is my belief that initially water retention is caused by the body holding on to water due to the effects of dianabol on the body's mineral balance, in particular the potassium/sodium balance. This coupled with the fact that dianabol cause estrogenic side effects, leads to a lot of water build-up, and as there is little we can do about the change in the bodies mineral balance, the only other thing we can do is try to reduce aromatisation, usually with Nolvadex (tamoxifen) or other anti-estrogens. This is not the only method though, by reducing the dose, less of the drug will aromatise, which leads to less estrogen and more importantly less water retention. Reducing the drug during a cycle would lead to estrogen levels dropping slowly, so we should start the cycle with a lower dose of 10-20mg each day.

Splitting the dosage when you are using a low dose is virtually pointless, as you will get a much smaller peak of the drug. So in this case it is best to take it in a single dose in the morning (preferably with grapefruit juice). Although this will not prevent suppression of natural testosterone, it may lessen it to a certain degree, as your body will still have lengthy periods later in the day when there is little testosterone circulating, and so it may still produce some.

Now if we look at cycle duration, 4-6 weeks seems too short to have any real effect at a low dose, but how can we use dianabol for longer without placing more risk on our liver? The solution is actually quite simple; by taking weekends off from the drug we will give our livers a break from processing the drug. Due to the short half-life any active substances will be out of our system within 24 hours of your last dose, now this may seem like it will cost you gains, but in actual fact it will cost you little or no losses in the long run as even though there is no active drug in the body the effects are still present i.e. extra intramuscular water, and a more anabolic mineral balance. These effects usually taper off over several days. This method will not however, help your natural testosterone to return from its inhibited state, as this process can take considerably longer. If we take weekends off and use a lower dose, we should in theory be able to use dianabol for 10 weeks with no problems. A simple bit of mathematics can show this point best:

6 weeks @25mg each day = 1050mg of Dianabol in total
10 weeks with weekends off @15mg each day = 750mg of Dianabol in total
So as you can see, by using this system your liver will actually process less dianabol than in a conventional cycle, add this to the fact that you can make gains for 10 weeks instead of 6, and with fewer side effects, and you get a very solid cycle.


Summary

This Cycle Theory can be applied in many different situations, for instance a beginner could use the dianabol on it's own for 10 weeks and gain very well. A more experienced steroid user could use this alongside an injectable cycle for very good gains too, getting the benefit of the initial quick gains of the Dianabol, with the slower but stronger gains of an injectable.

This cycle may seem to go against many of the current trends of dianabol use, but I believe that by using dianabol as a supplement to good training and nutrition you can make very good gains.

References

Effects of methandrostenolone on liver morphology and enzymatic activity. Nesterin MF, Budik VM, Narodetskaia RV, Solov'eva GI, Stoianova VG.
An experimental study of the hepatoprotective properties of phytoecdysteroids and Nerobol in carbon tetrachloride induce liver lesions. Syrov VN, Khushbaktova ZA, Nabiev AN.
Effects of methanedienone (methandrostenolone) on energy processes and carbohydrate metabolism in rat liver cells. Serakovskii S, Mats'koviak Iu.
Calcium, vitamin D and anabolic steroid treatment of aged bones: double-blind placebo-controlled long-term clinical trial. Inkovaara J, Gothoni G, Halttula R, Heikinheimo R, Tokola O.
Changes in body composition following therapy of osteoporosis with methandrostenolone. Mann V, Benko AB, Kocsar LT.
Radiomodifying effect of methandrostenolone on laryngeal cancer cells. Bordiushkov IuN, Kucherova TI, Kisliakova ND, Vagner VP, Zubkova TV.

2016年9月13日星期二

Test e, Deca, and Dbol

The purpose of this article is to educate the amateur bodybuilder on the correct set up of a powerful traditional bulking cycle; Test e, Deca, and Dbol. The use of Deca and Dbol has been long hailed as the mighty bulking cycle. Traditionally used as an off season cycle, the stack will do a wonderful job of adding muscle mass and letting the user come in at a heavier weight when reaching their goal body fat when cutting.




I have said it a million times before and I will say it again, testosterone is king. It is the foundation in which all cycles are built upon. Running any compound without the use of testosterone will leave you with hormone levels that are similar to a females. Testosterone Enanthate is a slower acting ester. With a 7 to 10 day half-life, it requires a less frequent dosing schedule to reach and maintain stable blood levels making it the better choice for beginner steroid users who may not be too fond of needles and do not want to do every day or every other day injections. Properly used, the injection schedule should be every 3.5 days on Monday and Thursday of the week. Dosages for testosterone enanthate range from a minimum of 400mg a week to 800mg a week for the average steroid user and cycles should be a minimum of 10 weeks due to the amount of time it takes to reach peak levels. More advanced users have been known to go over 1000mg a week, but one should be aware that it takes a lot of cycle experience to get to those levels. Longer estered testosterones like testosterone enanthate are known to cause more estrogen/aromatization side effects due to higher peak values over the course of the cycle. Proper AI/SERM precautions should be taken.


Deca has been the go to compound for bulking in bodybuilding amongst steroid users for years. Deca is a 19-nor compound. Its made from the same cloth as trenbolone. Consequently, it also shares many of the same issues as Tren. Being a 19-nor, deca is liver toxic. It also does not aromatize very well, but will cause a rise in progestin levels. Due to its ability to rise progestin levels, deca is known for causing libido issues or “deca dick.” Proper progestin/anti-estrogen drugs should be used to make sure you keep you from experiencing libido issues. It also will shut down natural testotsterone almost immediately with the first dose. Deca has as strong affinity to the androgen receptor and does great as an anabolic; it will raise both nitrogen retention and igf levels. Water retention does become an issue on deca, but the proper progestin drugs should keep it at bay. Deca is also known to help joint issues by storing water in the connective tissues and inproving collagen synthesis/mineral content. Some use the drug in low dosages such therapeutic effects. The recommended proper dosage for Deca is between 400-600mg a week. Though the ester connected to deca has a longer half life, its safe to inject deca on the same schedule as test e and c. In theory, deca can be injected once a week, but twice a week is the gold standard. Due to the highly suppressive nature of deca, its recommended that hcg be ran with the cycle.


Dbol is traditionally found in pill form. Like winstrol, Dbol is a 17aa oral steroid. 17aa orals are made the way they are to survive the first pass at the liver. Unfortunately, this makes dbol highly liver toxic (almost as toxic as winny). Dbol will also cause hypertension (a raise in blood pressure) so proper monitoring of your blood pressure should be maintained. Dbol is not the best at binding with the androgen receptor and most its effects are secondary. Dbol will suppress natural testosterone production. Many who are new to steroid use will try to do a Dbol only cycle. When dbol suppresses your natural production your levels start looking more like a females. Therefore, it should always be ran in a cycle with testosterone as a base. Dbol is said to be as strong as anadrol, though most will not see the same effects due to unequal dosages. Dbol is known as a kick start compound in cycles. Its ability to add weight comes on quickly and many people use it in the first 6 weeks of their cycle. Dosages range from 20-100mg a day, though an amateur user should stick to under 50mg to start.

The Cycle:

OK, lets set up a cycle for a first time user of these compounds combined. Keep in mind this isn’t a beginners cycle and stacking multiple compounds that you haven’t used in the same cycle may cause side effect and leave you wondering what the source of the issue was.

1). Testosterone Enanthate 300mg twice a week Week 1-12
2). Deca 200mg twice a week Week 1-12
3). Dbol 30-50mg a day Week 1-6
4). HCG 500iu a week (250iu twice a week) Week 1-12

Post Cycle Therapy

Clomid 100/50/50/50
Nolva 40/40/20/20


Trenbolone

History

Injectable trenbolone acetate was first released for use in the cattle industry in the 1980’s under the name Finajet. At the time, it contained the short acting acetate ester. This Trenbolone preparation was used to beef up cattle right before slaughter.



Trenbolone Hexahydrobenzylcarbonate is also known as Trenbolone Cyclohexylmethylcarbonate, these are two names for the exact same ester chain. This was the very first incarnation of Trenbolone ever made for human use by a pharmaceutical brand (Negma out of France). The manufacturer discontinued the product in 1997 and no other forms of human grade trenbolone have been available since then. All of the Trenbolone on the black market today is either veterinarian grade or made in underground laboratories.

In the late 1990’s when Parabolan was discontinued, the only, and last, human grade trenbolone product disappeared, so bodybuilders started extracting the trenbolone acetate hormone from cattle pellets sold under the brand Finaplix H. The pellets were not meant for human use, but rather as cattle implants to be punched behind the animal’s ear with a pellet gun. Creative bodybuilders used solvents and filters to extract the hormone from the pellets into a vial with injectable oil.

Trenbolone Profile


Trenbolone (Tren) has been regarded by many as one of the strongest and most effective steroids to change your physique quickly. This steroid is part of the 19-nor family of steroids which are characterized by a modification at the 19th position. Like trenbolone, another popular steroid in this 19-nor family is the very popular Nandrolone (Deca Durabolin and NPP), although the real-world actions of these two steroids are very different.

Scientist and steroid experts rate trenbolone as having an anabolic and androgenic score of 500/500, with Testosterone being the base at 100/100, all steroids are rated as compared to Testosterone. This rating of 500/500 means Trenbolone is five times (5x) more powerful than Testosterone in both its anabolic and androgenic effects. When talking about the anabolic effects of a steroid we are referring to the desirable effects like muscle building, nitrogen retention, cell repair and protein synthesis.

In addition, Trenbolone is five times (5x) more powerful than testosterone in its androgenic effects. When talking about the androgen properties of a steroid, we are referring to effects like muscle hardness, strength gains, increasing metabolism and, in some users, increased “aggression”.

Trenbolone’s chemical structure keeps it from being turned into female hormones, like estrogen, by the aromatase enzyme, so estrogen side-effects are not a concern. Trenbolone’s chemical ring alterations keep the aromatase enzyme from attaching to it and imparting its “feminizing” structural changes. Since trenbolone cannot aromatize and will not cause water-retention, the muscle gains made on trenbolone are very hard and dry; in fact, some users report a very noticeable drying effect from this steroid.

Esters and Injections

Injectable trenbolone has been commercially available with three different ester forms:

Trenbolone Acetate

Acetate is, by far, the most popular injectable version of trenbolone. This is mainly because it's been the easiest to obtain for most steroid users. For almost a decade, you couldn't visit a steroid forum without seeing threads about Finaplix-H conversions. This trend died down when UG labs came around and made costly and dangerous conversions unnecessary.

Although there is some debate about the half-life, acetate is usually injected every other day. Though, more hardcore users inject daily. I find this delivers marginally more results, but makes you feel like a pincushion.

Tren acetate is often stacked with testosterone propionate during cutting cycles; in addition, winstrol is considered synergetic with trenbolone.

Trenbolone Enanthate

Due to the popularity of testosterone enanthate, the word “enanthate” has give a boost to this tren preparation. Ironically, enanthate is clearly not as powerful as hexahydrobenzylcarbonate, but it sure as heck more popular. This just goes to show you that quality doesn't equal to popularity. Bodybuilders are usually doing things because they are popular, not because they are the most efficient way to get results.

Just like testosterone enanthate, tren enanthate is injected once a week due to the longer ester. Some users inject it twice a week for better results. Though, again, I find the increase in injections unnecessary; why? Simply because the added benefit is marginal at best.

Cycling tren enanthate is fairly simple. In general, it's stacked with testosterone enanthate or cypionate, while some guys add sustanon to the mix. Orals range from dianabol to anavar, depending on your goals.

Trenbolone Hexahydrobenzylcarbonate (Cyclohexylmethylcarbonate)

Since this ester is a tongue twister, we'll call it tren hex - to make reading simple. Tren hex is the famous parabolan preparation of trenbolone that was the “magic” steroid you could find in the 90s. I remember guys in the gym going crazy about getting their hands on some parabolan. It was like finding gold.

Why was it so popular? Anecdotally, I find tren hex to be a lot more powerful than acetate and enanthate. Since the real difference is in the esters, this might not make much sense. However, from personal use and from the numerous clients that I've had cycle parabolan, I can safely say this is the best trenbolone preparation on the market. Weekly injections deliver amazing results because it has a longer half-life. In addition, parabolan tends to build up in your system and really pushing you to reach peak performance after the first 2 weeks.

Stacking Trenbolone Hex (parabolan) can be a bit tricky, as most guys are using it for cutting. The best way is with a EOW (every other week) injection of a longer ester chain like testosterone cypionate, combined with EOD (every other day) injections of testosterone propionate. This allows for an interesting mix of testosterone and trenbolone build up in your system.

Oral Trenbolone has 2 main ester forms:

Acetate
Metribolone (methyltrienolone)
Although the base trenbolone hormone is available without an ester, this preparation has never gained popularity. There are two version of oral trenbolone available, one with an acetate ester and a methylated version called Metribolone (methyltrienolone), which has been altered at the 17th carbon position for oral use. Many bodybuilders question the real effectiveness of the acetate ester in oral preparations, with most athletes opting to inject trenbolone acetate as opposed to trying to take it orally.

Dosages and Uses

Dose ranges for trenbolone vary greatly depending on the ester preparation being used and the desired effects of the user. Trenbolone acetate is injected every day or every other day, in dosages ranging from 50mg per injection to, as high as, 200mg per injection.

Steroid users who inject the enanthate or hexahydrobenzylcarbonate version will usually inject the product weekly. The longer ester allows for a slower release of the hormone; thus, the steroid can be injected less often and in higher amounts. Athletes that use the longer ester versions of this product will usually inject between 200mg to 600mg of the product per week.

The oral version of trenbolone 17alpha-methyl-trenbolone, is so powerful and toxic, that only 0.5mg to 2mg of the product are needed daily to see and feel noticeable results.

Cycles

I will give you 4 cycles here, for the 4 most popular versions of trenbolone: oral, acetate, enanthate, hexahydrobenzylcarbonate.

Oral Metribolone (methyltrienolone) Cycle:
Week
Methyltrienolone
Winstrol
Cardarine
GW-501516
Ostarine
MK-2866
N2Guard
1
2mgs/ED
50mgs/ED
20mgs/ED
25mgs/ED
7caps/ED
2
2mgs/ED
50mgs/ED
20mgs/ED
25mgs/ED
7caps/ED
3
2mgs/ED
50mgs/ED
20mgs/ED
25mgs/ED
7caps/ED
4
2mgs/ED
50mgs/ED
20mgs/ED
25mgs/ED
7caps/ED

Trenbolone Acetate Cycle: this cycle is with ED – every day – injections, but can be modified for EOD – every other day – injections:
Week
Testosterone
Propionate
Trenbolone
Acetate
Anavar
Cardarine
GW-501516
Aromasin
N2Guard
1
50mgs/ED
50mgs/ED
40mgs/ED
20mgs/ED
12.5mgs/ED
7caps/ED
2
50mgs/ED
50mgs/ED
40mgs/ED
20mgs/ED
12.5mgs/ED
7caps/ED
3
50mgs/ED
50mgs/ED
40mgs/ED
20mgs/ED
12.5mgs/ED
7caps/ED
4
50mgs/ED
50mgs/ED
40mgs/ED
20mgs/ED
12.5mgs/ED
7caps/ED
5
50mgs/ED
50mgs/ED
40mgs/ED
20mgs/ED
12.5mgs/ED
7caps/ED
6
50mgs/ED
50mgs/ED
40mgs/ED
20mgs/ED
12.5mgs/ED
7caps/ED
7
50mgs/ED
50mgs/ED

20mgs/ED
12.5mgs/ED
7caps/ED
8
50mgs/ED
50mgs/ED

20mgs/ED
12.5mgs/ED
7caps/ED
9
50mgs/ED
50mgs/ED

20mgs/ED
12.5mgs/ED
7caps/ED
10
50mgs/ED
50mgs/ED

20mgs/ED
12.5mgs/ED
7caps/ED
Trenbolone Enanthate cycle – this cycle is mainly injectables without an oral kickstart:
Week
Testosterone
Enanthate
Trenbolone
Enanthate
Cardarine
GW-501516
Aromasin
N2Guard
1
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
2
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
3
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
4
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
5
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
6
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
7
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
8
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
9
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
10
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
11
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
Trenbolone Hexahydrobenzylcarbonate (Cyclohexylmethylcarbonate) cycle – also no oral kickstart:
Week
Testosterone
Cypionate
Trenbolone
Hexa
Cardarine
GW-501516
Aromasin
N2Guard
1
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
2
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
3
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
4
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
5
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
6
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
7
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
8
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
9
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
10
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
11
500mgs/EW
400mgs/EW
20mgs/ED
12.5mgs/ED
7caps/ED
Half-life

On it’s own, the base trenbolone hormone has a half-life of about 6-8 hours. Although not many bodybuilders use the base hormone. Most athlete are injecting a version of trenbolone that has an ester chain attached to it, and it is not until plasma lipases in the blood stream cleave off the ester chain that trenbolone is free to interact with androgen receptors in muscle cells. The active half-life of the acetate ester version is of about 48 hours, while the enanthate version is about 5-7 days. The Hexahydrobenzylcarbonate (Cyclohexylmethylcarbonate) ester chain being the longest at 8-10 days. Though, due to the lack of scientific consensus, some of these figures can be off by about 10-20%.

Side Effects

The most common side-effects reported by trenbolone users are:

Aggression and temper.
Night Sweats.
Decreased cardio endurance.
Dark colored urine.
Loss of hair, where there is no genetic predisposition for it.
Inability to reach a climax during intercourse, or sometimes total impotence.
Gynecomastia has been reported in rare cases.
Coughing spells or shortness of breath following an injection. Also known as “tren cough”.

Managing Side-effects

Interestingly, there is a lot of information about the negative side-effects of trenbolone, but there is little information about combating those sides. Let's address the first, and most prominent, side effect: “tren cough” and cardio problem. This is by far the biggest complaint with tren use, which can be mitigated by adding cardarine (gw-501516) and ostarine (mk-2866) to your tren cycle.


The second problem with tren is the possibility of prolacin side effects, which are the cause of possible “impotence” and problems in the bedroom, as well as gynecomastia (bitch tits). This can easily be overcome by the use of two products: a) Cabergoline (Dostinex), which is an anti-prolactin drug and b) HCGenerate, which helps you keep libido going during a cycle.

The third problem, and one of the deadliest, is the issue with your liver and kidneys while using trenbolone. This is one of the most serious issues, and it's never addressed properly by most steroid users. To fix this, you need to add N2Guard to your cycle. It will help protect your liver, kidneys and organs from the harsh tren sides.